There are no registration fees for the RECOMB-SEQ 2020 VIRTUAL Conference. Registration is still required.


Paola Bonizzoni
Zamin Iqbal


Proceedings and Overlay Track
Paper submission opens: December 9, 2019
Paper submission deadline: Extended to January 20, 2020
Paper acceptance decision: February 20, 2020

Short talks and posters track
Abstract submission opens: January 22, 2020
Abstract submission deadline: March 23, 2020
Abstract acceptance decision: April 3, 2020


A wave of technologies transformed sequencing over a decade ago into the high-throughput era, demanding research in new computational methods to analyze this data. The applications of sequencing have continually expanded. The Tenth RECOMB Satellite Workshop on Massively Parallel Sequencing (RECOMB-Seq) brings together leading researchers in computational genomics and genomic biology to discuss emerging frontiers in algorithm development for massively parallel sequencing data. The emphasis of all contributed work will be on applying statistical and algorithmic approaches to improve sequence data management, analysis, and interpretation.

Topics of Interest (including but not limited to)
Read mapping for second and third generation sequencing technologies
Techniques for managing (e.g., data compression) and visualizing massive amount of sequencing data
Consensus sequence construction
Discovery and genotyping of genomic variants, including SNPs, indels, and structural variants
Local and de novo sequence assembly Methods for analysis of RNA sequencing (RNA-seq) data, including RNA expression, novel transcript assembly and splicing
Methods for novel sequencing technologies such as single-cell sequencing, linked-read sequencing and Hi-C
Translational applications of sequencing data, including cancer genomics and infectious disease
Epigenetics and gene regulation, including ChIP-seq analysis, methylation profiling, and histone modification
Pan-genomics and genome graphs
Optical mapping


We solicit contributions in four different categories as follows:
Proceedings track
This track solicits manuscripts describing original work on computational aspects of genomic research involving massively parallel sequencing. All manuscripts in this track will be considered for publication in a special issue of the journal iScience. At the time of submission, and for the entire review period, the work should not be under review by any other conference or scientific journal. Authors of manuscripts that are selected for oral presentation at RECOMB-seq after review but are not deemed suitable for iScience (or if the authors do not select publication in iScience) will be required to host their manuscript on a public preprint server.

Overlay track
Manuscripts submitted to this track will be reviewed by the program committee and selected submissions will be invited for oral presentation. The manuscript should be hosted on a public preprint server (bioRxiv, arXiv or PeerJ) at the time of submission. There are no specific formatting or page length requirements, but the paper should generally be formatted in a way that emphasizes the methodological contributions. Manuscripts can be submitted elsewhere at the same time but should not be published or in press at the time of submission.

Highlights Track
This track is for papers that have already been published or are in press. This track is joint with the main conference (deadline January 31, 2020). For instructions and more details, see the RECOMB 2020 website.

Abstracts for short talks or posters
Regular abstracts describing original work, including software applications. These will be considered for short oral presentations or posters. A 1-2 page abstract describing the methods and key results should be submitted via the EasyChair system.


All submissions to the proceedings track will be simultaneously considered for publication in a special issue of the journal iScience, if the authors agree. iScience is an open-access journal published by Cell Press for original research in the life, physical, and earth sciences.

In addition to the program committee of RECOMB-seq, editors of iScience will evaluate the papers for biological impact and suitability for publication. In particular, the following criteria will be used to evaluate the biological relevance:
- Can inputs be found through experiments?
- Can outputs be used directly in future experiment or analysis?
- Can outputs be obtained through well-established methodology for less cost?
- Is methodology proposed applicable in useful settings?
- Do biological data support the study?
- Is biological variability sufficiently accounted for?

Authors who do not wish their manuscript to be considered for iScience should use the overlay track for submission. Publication in iScience is subject to an Open Access charge of $3000.
Reduced Open Access charges for authors in developing countries and others in financial hardship are available.